Monkeypox confirmed in 16 countries Four times as many countries outside Africa have reported monkeypox this month as have in the previous 50 years.

Although scientists rarely spot monkeypox outside of the 11 countries in Africa that have reported cases, a recent outbreak has led the disease to be identified in a dozen European countries, along with the U.S., Australia, Canada and Israel.

At least 160 confirmed cases of monkeypox have been reported this month in non-African countries, according to, a group that gathers infectious disease data. All but 10 of those cases have been in Europe: 56 in the United Kingdom, 41 in Spain, 37 in Portugal and single-digit case counts in Austria, Belgium, Denmark, France, Germany, Italy, the Netherlands, Sweden and Switzerland.

Four times as many countries outside of Africa have reported monkeypox this month than have in the previous 50 years. Until recently, the largest outbreak in the Western Hemisphere was in 2003, when pet prairie dogs infected 47 people in the U.S.

“What this really marks is the emergence of the most important poxvirus since the eradication of smallpox now in the Western Hemisphere,” said Anne Rimoin, an epidemiology professor at UCLA Fielding School of Public Health. “Of course, we worry if we start to see additional spread of this virus and then it becomes established in the human population.”

Many of the people who’ve gotten monkeypox in the current outbreak have no history of recent travel to Africa or known exposure to an infected person. Cases have largely been identified among young men who have sex with men, leading experts to believe that the disease is being spread through skin-to-skin contact, perhaps from exposure to rashes and lesions during sexual activity, World Health Organization officials said Monday.

But the DRC and Nigeria have both seen a rise in monkeypox cases. The DRC reported more than 18,000 confirmed or suspected monkeypox cases from 2010 to 2019, up from about 10,000 from 2000 to 2009, and more than 6,000 suspected cases in 2020. Nigeria has reported more than 200 confirmed cases since 2017 and more than 500 suspected ones, according to the WHO.

“All of the imported cases outside of Africa that have occurred since 2018 have been from Nigeria,” said Dr. Agam Rao, a medical officer at the Centers for Disease Control and Prevention’s Division of High Consequence Pathogens and Pathology.

The recent cases belong to the West African clade of monkeypox, which is relatively mild: Around 1 percent of people who contract it die, compared to 10 percent of percent with the Congo Basin clade, according to the WHO.

The risk to the general population is low, Rimoin said, but the outbreak nonetheless shows that infectious diseases rarely stay in one location.

“This is a very important reminder that an infection anywhere is potentially an infection everywhere,” she said.